The Ly108 antibody from MyBioSource.com is a Mouse Monoclonal antibody. The Ly108 antibody has been validated for the following applications: Flow Cytometry, Functional Assay, and Immunohistochemistry.
Description
Mouse monoclonal Ly108 antibody
The 13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6. Mouse Ly108 is also known as NTB-A, and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions.Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested